Essays on Metabolism

Epinephrine auto-injection, also known as adrenaline, or the company that most people are familiar with is the EpiPen. This molecular compound is making a great impact on the lives of those who have very intense allergies, the most common allergens are peanuts, bees and shellfish….

Abstract Background: The Japanese quail, Coturnix japonica has been shown to be an efficient animal model for studying the retinal disorders. The retinal pigment epithelium (RPE) cells of this animal model and human monocyte cells were used to determine the conditions under which irradiation of…

One of the most common supplements taken when people are trying to build lean muscle is whey protein. I took whey protein when I was in high school because I thought it would help me become stronger. Originally my way of knowing this was a…

Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism Introduction Tamoxifen is an anticancer prodrug effective against breast tumors for women that is activated through hepatic metabolism. Although this drug has been proven to be effective for reducing recurrences, inter-individual…

While it is undoubtedly a blessing to be armed with such a wealth of information in regards to healthcare, such a staggering volume of literature may have one wondering how to start learning more about a particular treatment. The following pages explore ten different peer-reviewed…

Abstract There is a significant gap in the literature as to patient experiences surrounding metabolic syndrome. The purpose of this pilot study was to understand the knowledge of patients with metabolic syndrome surrounding their condition and self-reported barriers to management. Individuals with metabolic syndrome were…

Metabolomics – the novel science that evaluates all low molecular weight metabolites in a biological system, provides new data about pathogenetic mechanisms of diseases, including endocrine tumors. Although the metabolomic analysis in pituitary pathology is at an early stage, it seems to be a promising…

In previous papers, multiple sclerosis (MS) has been defined as a progressive neurodegenerative disease. MS advancement has been divided into two stages: relapse emitting stage (RRMS) and secondary progressive stage (SPMS). Previous studies have shown that mitochondrial deficits can affect cortical pathology that can in…

HOST: DRUG METABOLIZING ENZYME Human xenobiotic metabolism generally converts non polar compounds into hydrophilic, high molecular weight compounds so that they can be more readily excreted. The process occurs in hepatic circulation as follows: In phase I, enzymes such as Cytochrome P450 oxidases, introduce a…