Pneumonia is a Fatal Disease


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Streptococcus Pneumoniae

A wide variety of bacteria, viruses, and fungi can cause Pneumonia which is present in the air we breathe. An important step in getting the proper treatment is identifying the cause of your pneumonia. Bacterial pneumonia is the most common type of pneumococcal pneumonia. The Streptococcus pneumoniae germ that normally lives in the upper respiratory tract causes Pneumococcal pneumonia. 900,000 Americans are infected by it every year. After you’ve had a viral cold or the flu you can develop bacterial pneumonia or it can develop on its own. Just one part, or lobe, of a lung, is often affected by bacterial pneumonia. This condition is called lobar pneumonia.

Antibiotic Treatment

The first-line antibiotic that might be selected for pneumonia is amoxicillin. If the patient is not recovered from amoxicillin alone then other appropriate antibiotics that can be selected are the fluoroquinolone antibiotics such as levofloxacin and azithromycin or combined therapy of a beta-lactam such as amoxicillin/clavulanate or amoxicillin with a macrolide antibiotic.

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Mechanism of Action

Located inside the bacterial cell wall is penicillin-binding protein 1A to which amoxicillin binds. The penicillin-sensitive transpeptidase C-terminal domain is acylated by penicillin, by opening the lactam ring. The formation of a cross-link of two linear peptidoglycan strands is prevented by the inactivation of the enzyme, inhibiting the third and last stage of bacterial cell wall synthesis. Bacterial cell wall autolytic enzymes such as autolysins mediate the lysis of cell and it is possible that amoxicillin interferes with an autolysin inhibitor. So basically, bactericidal activity is exerted by amoxicillin via inhibition of bacterial cell wall synthesis by binding one or more of the penicillin-binding proteins. The bacterial autolytic effect caused by amoxicillin is by inhibition of certain PBPs related to the activation of a bacterial autolytic process.

Counselling Points

Try to quit smoking as it makes you more susceptible to respiratory infections, especially pneumonia. Cover your coughs and sneezes. Regularly wash your hands with soap and water. Promptly dispose of used tissues. Get regular exercise, get enough rest, and eat a healthy diet. To strengthen your immune system, maintain a healthy lifestyle. Following are some necessary tips can help you recover more quickly and decrease your risk of complications:

Take Your Medicine as Prescribed

The entire course of any medications should be taken as your doctor prescribed for you. Your lungs may continue to harbor bacteria that can multiply and cause your pneumonia to recur if you stop taking medication too soon.

Get Plenty of Rest

Don’t go back to work until after you stop coughing up mucus and your temperature returns to normal. Be careful not to overdo it even when you start to feel better. It’s better not to jump back into your routine until you are fully recovered because pneumonia can recur. Ask your doctor if you’re not sure.

Stay Hydrated

To help loosen mucus in your lungs drink plenty of fluids, especially water.

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